*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH6494000
CHEMICAL NAME           : Theophylline, 7-(2-((3-pyridylmethyl)amino)ethyl)-
CAS REGISTRY NUMBER     : 10001-43-1
BEILSTEIN REFERENCE NO. : 1167438
REFERENCE               : 5-26-14-00015 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H18-N6-O2
MOLECULAR WEIGHT        : 314.39
WISWESSER LINE NOTATION : T56 BN DN FNVNVJ F1 H1 B2M1- CT6NJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   3,7-Dihydro-1,3-dimethyl-7-(2-((3-pyridinylmethyl)amino)ethyl)-1H-purine
     -2,6-dione
   * ES 771
   * 7-(beta-3'-Picolylaminoethyl)theophylline
   * Pimefylline
   * Pimephylline
   * 7-(2-((3-Pyridylmethyl)amino)ethyl)theophylline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PAHEAA Pharmaceutica Acta Helvetiae.  (Schweizerische Apothekerzeitung,
   Postfach 3006, CH3000 Bern, 7, Switzerland)  V.1-    1926-
   Volume(issue)/page/year: 48,133,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 402 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PAHEAA Pharmaceutica Acta Helvetiae.  (Schweizerische Apothekerzeitung,
   Postfach 3006, CH3000 Bern, 7, Switzerland)  V.1-    1926-
   Volume(issue)/page/year: 48,133,1973
 
                            *** END OF RECORD ***