*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : XH9200000 CHEMICAL NAME : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(butylthio acetamido)- CAS REGISTRY NUMBER : 6192-29-6 BEILSTEIN REFERENCE NO. : 0044346 REFERENCE : 4-27-00-05887 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C14-H22-N2-O4-S2 MOLECULAR WEIGHT : 346.50 WISWESSER LINE NOTATION : T45 ANV ESTJ CMV1S4 F1 F1 GVQ COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Butylmercaptomethylpenicillin * n-Butylthiomethylpenicillin * Penicillin BT *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intracerebral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 101 mg/kg TOXIC EFFECTS : Brain and Coverings - other degenerative changes REFERENCE : JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 34,126,1949 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intracerebral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 11500 ug/kg TOXIC EFFECTS : Brain and Coverings - other degenerative changes REFERENCE : JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 34,126,1949 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 56 mg/kg TOXIC EFFECTS : Brain and Coverings - other degenerative changes REFERENCE : JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 34,126,1949 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intracerebral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 15600 ug/kg TOXIC EFFECTS : Brain and Coverings - other degenerative changes REFERENCE : JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 34,126,1949 *** END OF RECORD ***