*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : XH9801000 CHEMICAL NAME : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-((phenylacetyl) amino)-2S-(2-alpha,5-alpha,6-beta))-, compd. with (1R-(1-alpha(1R*,4aS*,10aR*),4a-beta,10a- alpha))-N,N'-bis((1,2,3,4,4a,9,10,10a-octahydro-1,4a- dimethyl-7-(1-methyle thyl)-1- phenanthrenyl)methyl)-1,2-ethanediamine (2:1) CAS REGISTRY NUMBER : 3344-16-9 LAST UPDATED : 199712 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C42-H64-N2.2C16-H18-N2-O4-S MOLECULAR WEIGHT : 1265.92 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Compocillin * Hydrabamine penicillin G * Penicillin G compd. with N,N'-bis(dehydroabietyl)ethylenediamine (2:1) * Penicillin G hydrabamine *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >4 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 5,315,1955 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 450 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 2,133,1954/1955 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : >1254 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 2,133,1954/1955 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - cat DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 2,133,1954/1955 TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ABANAE Antibiotics Annual. (New York, NY) 1953-60. For publisher information, see AMACCQ. Volume(issue)/page/year: 2,133,1954/1955 *** END OF RECORD ***