*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XH9802300
CHEMICAL NAME           : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid,
                          3,3-dimethyl-7-oxo-6-((phenylacetyl) amino)-,
                          (2S-(2-alpha,5-alpha,6-beta))-, compd. with
                          N-((4-methoxyphenyl)methyl)-
                          N',N'-dimethyl-N-2-pyrimidinyl-1,2-ethanediamine
LAST UPDATED            : 198909
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C16-H18-N2-O4-S.C16-H22-N4-O
MOLECULAR WEIGHT        : 620.84
SYNONYMS/TRADE NAMES :
   * Thonzylamine-penicillin G
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 178 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   52,83S,1956
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 71200 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   52,83S,1956
 
                            *** END OF RECORD ***