*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : XI0100000 CHEMICAL NAME : 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 3,3-dimethyl-7-oxo-6-(((2-propenylthio) acetyl)amino)- CAS REGISTRY NUMBER : 87-09-2 BEILSTEIN REFERENCE NO. : 0044307 REFERENCE : 4-27-00-05887 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C13-H18-N2-O4-S2 MOLECULAR WEIGHT : 330.45 WISWESSER LINE NOTATION : T45 ANV ESTJ CMV1S2U1 F1 F1 GVQ COMPOUND DESCRIPTOR : Drug Human SYNONYMS/TRADE NAMES : * Allylmercaptomethylpenicillin * Allylmercaptomethylpenicillinic acid * Allylthiomethylpenicillin * Almecillin * Cer-O-Cillin * Penicillin AT * Penicillin O *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Multiple routes SPECIES OBSERVED : Human - woman DOSE/DURATION : 35827 ug/kg/6D-I TOXIC EFFECTS : Vascular - structural changes in vessels REFERENCE : JOALAS Journal of Allergy. (St. Louis, MO) V.1-47, 1929-71. For publisher information, see JACIBY. Volume(issue)/page/year: 31,455,1960 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intracerebral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 45 mg/kg TOXIC EFFECTS : Brain and Coverings - other degenerative changes REFERENCE : JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 34,126,1949 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intracerebral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 6490 ug/kg TOXIC EFFECTS : Brain and Coverings - other degenerative changes REFERENCE : JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 34,126,1949 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 38 mg/kg TOXIC EFFECTS : Brain and Coverings - other degenerative changes REFERENCE : JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 34,126,1949 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intracerebral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 5610 ug/kg TOXIC EFFECTS : Brain and Coverings - other degenerative changes REFERENCE : JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 34,126,1949 *** END OF RECORD ***