*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XI0372700
CHEMICAL NAME           : 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic
                          acid, 7-(((3,5-dichloro-4-oxo-1(4H)-
                          pyridinyl)acetyl)amino)-3-(((5-methyl-1,3,4-thiadiazo
                          l-2-yl)thio)methyl)-8 -oxo-, (6R-trans)-
CAS REGISTRY NUMBER     : 56187-47-4
BEILSTEIN REFERENCE NO. : 1097746
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H15-Cl2-N5-O5-S3
MOLECULAR WEIGHT        : 548.46
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Cefazedone
   * Refosporene
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 88 mg/kg/17W-I
TOXIC EFFECTS :
   Blood - normocytic anemia
   Blood - thrombocytopenia
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   90,135,1987
 
                            *** END OF RECORD ***