*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XI0373000
CHEMICAL NAME           : 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic
                          acid, 7-(2-((N,N'-diisopropylamidino)thio)
                          acetamido)-3-(hydroxymethyl)-8-oxo-, acetate
CAS REGISTRY NUMBER     : 33075-00-2
LAST UPDATED            : 199406
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H28-N4-O6-S2
MOLECULAR WEIGHT        : 472.63
WISWESSER LINE NOTATION : T46 ANV ES GUTJ CMV1SYMY1&1&UNY1&1 G1OV1 HVQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Cefathiamidine
   * 7-(alpha-((N,N'-Diisopropylamidino)thio)acetylamino)cephalosporanic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1260 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CMJODS Chinese Medical Journal (Beijing, English Edition).  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 
     1975-    Adopted vol. no. 92 in 1979.  Volume(issue)/page/year: 92,26,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 720 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CMJODS Chinese Medical Journal (Beijing, English Edition).  (China
   International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1- 
     1975-    Adopted vol. no. 92 in 1979.  Volume(issue)/page/year: 92,26,1979
 
                            *** END OF RECORD ***