*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XI0373900
CHEMICAL NAME           : 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic
                          acid, 7-(((((4-ethyl-2,3-dioxo-1-
                          piperazinyl)carbonyl)amino)(4-hydroxyphenyl)acetyl)am
                          ino)-3-(((1-methyl-1H -tetrazol-5-yl)
                          thio)methyl)-8-oxo-, (6R-(6-alpha,7-beta(R*)))-
CAS REGISTRY NUMBER     : 62893-19-0
OTHER CAS REGISTRY NOS. : 72448-63-6
BEILSTEIN REFERENCE NO. : 0603333
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C25-H27-N9-O8-S2
MOLECULAR WEIGHT        : 645.73
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Cefobid
   * Cefoperazine
   * Cefoperazone
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 30 gm/kg
SEX/DURATION            : male 30 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   8,280,1987

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - X5275
       No. of Facilities: 7 (estimated)
       No. of Industries: 1
       No. of Occupations: 2
       No. of Employees: 307 (estimated)
       No. of Female Employees: 251 (estimated)

 
                            *** END OF RECORD ***