*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : XI3900000 CHEMICAL NAME : 1,3,4-Thiadiazole, 2-ethylamino- CAS REGISTRY NUMBER : 13275-68-8 BEILSTEIN REFERENCE NO. : 0110762 REFERENCE : 4-27-00-08053 (Beilstein Handbook Reference) LAST UPDATED : 199701 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C4-H7-N3-S MOLECULAR WEIGHT : 129.20 WISWESSER LINE NOTATION : T5NN DSJ CM2 COMPOUND DESCRIPTOR : Drug Reproductive Effector SYNONYMS/TRADE NAMES : * CL 19217 4090L 7-5525 * 2-Ethylaminothiadiazole * 2-Ethylamino-1,3,4-thiadiazole * N-Ethyl-1,3,4-thiadiazol-2-amine * NSC 4730 * 1,3,4-Thiadiazol-2-amine, N-ethyl- * X 197 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CPCHAO Clinical Proceedings of the Children's Hospital of the District of Columbia. (Washington, DC) V.1-27, 1971. For publisher information, see CPNMAQ. Volume(issue)/page/year: 18,307,1962 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JHMJAX Johns Hopkins Medical Journal. (Baltimore, MD) V.120-151, 1967-82. Discontinued. Volume(issue)/page/year: 130,95,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 795 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE : 150 mg/kg SEX/DURATION : female 10-11 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - musculoskeletal system REFERENCE : JHMJAX Johns Hopkins Medical Journal. (Baltimore, MD) V.120-151, 1967-82. Discontinued. Volume(issue)/page/year: 130,95,1972 *** STATUS IN U.S. *** EPA TSCA Section 8(b) CHEMICAL INVENTORY *** END OF RECORD ***