*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XI4816000
CHEMICAL NAME           : 1,3,4-Thiadiazole-2(3H)-thione,
                          5,5'-(methylenediimino)bis-
CAS REGISTRY NUMBER     : 79319-85-0
LAST UPDATED            : 198703
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C5-H6-N6-S4
MOLECULAR WEIGHT        : 278.41
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Chuan HUA 018
   * N,N'-Methylene-bis(2-amino-5-sulfhydryl-1,3,4-thiadiazole)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4640 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZYDXDM Zhejiang Yike Daxue Xuebao.  Journal of Zhejiang Medical University.
   (Zhejiang Yike Daxue, Yan'an Lu, Hanzhou, Zhejiang, Peop. Rep. China)  V.1-
   1972(?)-  Volume(issue)/page/year: 14,267,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6810 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZYDXDM Zhejiang Yike Daxue Xuebao.  Journal of Zhejiang Medical University.
   (Zhejiang Yike Daxue, Yan'an Lu, Hanzhou, Zhejiang, Peop. Rep. China)  V.1-
   1972(?)-  Volume(issue)/page/year: 14,267,1985
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 500 umol/L
REFERENCE :
   ZYDXDM Zhejiang Yike Daxue Xuebao.  Journal of Zhejiang Medical University.
   (Zhejiang Yike Daxue, Yan'an Lu, Hanzhou, Zhejiang, Peop. Rep. China)  V.1-
   1972(?)-  Volume(issue)/page/year: 14,267,1985
 
                            *** END OF RECORD ***