*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XI4819900
CHEMICAL NAME           : 1,3,4-Thiadiazol-2(3H)-one, 5-(2-methylphenyl)-,
                          hydrazone, monohydrochloride
CAS REGISTRY NUMBER     : 65871-41-2
LAST UPDATED            : 198910
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C9-H10-N4-S.Cl-H
MOLECULAR WEIGHT        : 242.75
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5-(2-Methylphenyl)-1,3,4-thiadiazol-2(3H)-one hydrazone hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Vascular - BP lowering not characterized in autonomic section
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 31,902,1988
 
                            *** END OF RECORD ***