*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : XJ1261700 CHEMICAL NAME : 4H-1,3-Thiazin-4-one, tetrahydro-2-phenyl- CAS REGISTRY NUMBER : 72286-34-1 BEILSTEIN REFERENCE NO. : 0149651 REFERENCE : 4-27-00-02758 (Beilstein Handbook Reference) LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C10-H11-N-O-S MOLECULAR WEIGHT : 193.28 COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Tetrahydro-2-phenyl-4H-1,3-thiazin-4-one *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >2 gm/kg TOXIC EFFECTS : Vascular - BP lowering not characterized in autonomic section REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 122,517,1957 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1500 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - ataxia Vascular - BP lowering not characterized in autonomic section REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 122,517,1957 *** END OF RECORD ***