*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ2983000
CHEMICAL NAME           : Thiazole, 4,5-bis(4-methoxyphenyl)-2-trifluoromethyl-
CAS REGISTRY NUMBER     : 70529-35-0
BEILSTEIN REFERENCE NO. : 1161179
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H14-F3-N-O2-S
MOLECULAR WEIGHT        : 365.39
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4,5-Bis(4-methoxyphenyl)-2-trifluoromethylthiazole
   * Itazigrel
   * LY 108048
   * U 53059
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4659726
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THHADQ Thrombosis and Haemostasis.  (F.K. Schattauer Verlag, Postfach
   104545, D-70040 Stuttgart, Germany)  V.35-    1976- Volume(issue)/page/year:
   46,26,1981
 
                            *** END OF RECORD ***