*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ3850000
CHEMICAL NAME           : Thiazole, 5-(2-chloroethyl)-4-methyl-
CAS REGISTRY NUMBER     : 533-45-9
BEILSTEIN REFERENCE NO. : 0114244
REFERENCE               : 4-27-00-00990 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C6-H8-Cl-N-S
MOLECULAR WEIGHT        : 161.66
WISWESSER LINE NOTATION : T5N CSJ D2G E1
SYNONYMS/TRADE NAMES :
   * Chlorethiazol
   * Chlorethiazole
   * Chlormethiazol
   * Chlormethiazole
   * 5-(2-Chloroethyl)-4-methylthiazole
   * Chloro-S.C.T.Z.
   * Clomethiazole
   * Clomethiazolum
   * Distraneurin
   * Emineurina
   * 4-Methyl-5-(beta-chloroethyl)thiazole
   * Somnevrin
   * WY 1485
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2110 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 7,167,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 190 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APSXAS Acta Pharmaceutica Suecica.  (Apotekarsocieteten-Farmacevtiska
   Foereningen, Box 1136, S-111, 81 Stockholm, Sweden)  V.1-    1964-
   Volume(issue)/page/year: 8,39,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 94 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APSXAS Acta Pharmaceutica Suecica.  (Apotekarsocieteten-Farmacevtiska
   Foereningen, Box 1136, S-111, 81 Stockholm, Sweden)  V.1-    1964-
   Volume(issue)/page/year: 7,423,1970
 
                            *** END OF RECORD ***