*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : XJ5131750 CHEMICAL NAME : delta(sup 2,alpha)-Thiazolidineacetic acid, 3-ethyl-4-oxo-5-piperidino-, ethyl ester, (Z)- CAS REGISTRY NUMBER : 63250-48-6 LAST UPDATED : 199312 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C14-H22-N2-O3-S MOLECULAR WEIGHT : 298.44 WISWESSER LINE NOTATION : T5SYNV EHJ BU1VO2 C2 E- AT6NTJ -Z COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Acetic acid, (3-ethyl-4-oxo-5-(1-piperidinyl)-2-thiazolidinylidene)-, ethyl ester, (Z)- * Z-(3-Aethyl-4-oxo-5-piperidino-thiazolidin-2-yliden)-essigsaure-aethyles ter * Ethyl 3-ethyl-4-oxo-5-piperidino-delta(sup 2,alpha)-thiazolidineacetate * Ethyl (Z)-(3-ethyl-4-oxo-5-piperidinothiazolidin-2-ylidene)acetate * cis-2-(3-Ethyl-4-oxo-5-piperidino-2-thiazolidinylidene)acetic acid * (3-Ethyl-4-oxo-5-(1-piperidinyl)-2-thiazolidinylidene)acetic acid ethyl ester * Go 919 * Piprozolin * Piprozoline * Probilin * W 3699 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 3256 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,467,1977 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1070 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,467,1977 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 200 gm/kg/26W-C TOXIC EFFECTS : Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,493,1977 *** END OF RECORD ***