*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ5811700
CHEMICAL NAME           : 2,4-Thiazolidinedione,
                          5-((3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl)methyl
                          ene)-
CAS REGISTRY NUMBER     : 127378-46-5
LAST UPDATED            : 199706
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H23-N-O3-S
MOLECULAR WEIGHT        : 333.48
SYNONYMS/TRADE NAMES :
   *   5-((3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl)methylene)-2,4-thiazolidi
     nedione
   * CI 987
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Primate - monkey
DOSE/DURATION           : 4200 mg/kg/2W-I
TOXIC EFFECTS :
   Behavioral - food intake (animal)
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   TOXID9 Toxicologist.  (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway,
   Akron, OH 44311) V.1-    1981-  Volume(issue)/page/year: 13,37,1993
 
                            *** END OF RECORD ***