*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XJ7030100
CHEMICAL NAME           : Thiazolium,
                          3-((4-(dibutylamino)-2-methyl-5-pyrimidinyl)methyl)-5
                          -(2-hydroxyethyl)- 4-methyl-, chloride
CAS REGISTRY NUMBER     : 54690-41-4
LAST UPDATED            : 198405
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H33-N4-O-S.Cl
MOLECULAR WEIGHT        : 413.08
WISWESSER LINE NOTATION : T6N CNJ B1 DN4&4 E1- AT5K CSJ D2Q E1 &G
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Bisbutitiamine
   * Bisbutyl thiamine
   * Bisbutythiamin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,608,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 240 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,608,1982
 
                            *** END OF RECORD ***