*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XM7250000
CHEMICAL NAME           : 3-Thiophenamine, tetrahydro-N-methyl-N-nitroso-,
                          1,1-dioxide
CAS REGISTRY NUMBER     : 13256-21-8
LAST UPDATED            : 199106
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C5-H10-N2-O3-S
MOLECULAR WEIGHT        : 178.23
WISWESSER LINE NOTATION : T5SWTJ CN1&NO
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * 3-(N-Nitrosomethylamino)sulfolan
   * Phenamine, tetrahydro-N-methyl-N-nitroso-3-thio-, 1,1-dioxide
   * N-Nitrosomethylaminosulfolane
   * Tetrahydro-N-methyl-N-nitroso-3-thiophenamine 1,1-dioxide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ZEKBAI Zeitschrift fuer Krebsforschung.  (Berlin, Fed. Rep. Ger.)  V.1-75,
   1903-71.  For publisher information, see JCROD7.  Volume(issue)/page/year:
   69,103,1967
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2700 mg/kg/48W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 19,1077,1969
 
                            *** END OF RECORD ***