*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XK6420000
CHEMICAL NAME           : 1-Thiochromone, 3-(chloromethyl)-, 1,1-dioxide
CAS REGISTRY NUMBER     : 77694-48-5
LAST UPDATED            : 199707
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C10-H7-Cl-O3-S
MOLECULAR WEIGHT        : 242.68
WISWESSER LINE NOTATION : T66 BSW EVJ D1G
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 4H-1-Benzothiopyran-4-one, 3-(chloromethyl)-, 1,1-dioxide
   * 3-Chloromethylthiochromone-1,1-dioxide
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 30 mg/kg/3D
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 71,857,1982
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 30 mg/kg/3D
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 71,857,1982
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Ascites tumor
DOSE/DURATION           : 360 umol/L
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 71,857,1982
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Rodent - mouse Ascites tumor
DOSE/DURATION           : 360 umol/L
REFERENCE :
   JPMSAE Journal of Pharmaceutical Sciences.  (American Pharmaceutical Assoc.,
   2215 Constitution Ave., NW, Washington, DC 20037)  V.50-    1961-
   Volume(issue)/page/year: 71,857,1982
 
                            *** END OF RECORD ***