*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XN3881910
CHEMICAL NAME           : 2H-Thiopyran-4-ol,
                          tetrahydro-3-((dimethylamino)methyl)-4-(3-hydroxyphen
                          yl)-, hydrochloride, trans-(+-)-
CAS REGISTRY NUMBER     : 119558-39-3
LAST UPDATED            : 199707
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H21-N-O2-S.Cl-H
MOLECULAR WEIGHT        : 303.88
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (+-)-trans-4-(3-Hydroxyphenyl)-3-(dimethylaminomethyl)thiacyclohexan-4-ol 
    hydrochloride
   *   (+-)-trans-Tetrahydro-3-((dimethylamino)methyl)-4-(3-hydroxyphenyl)-2H-t
     hiopyran-4-ol HCl
   * VUFB-15585
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 430 mg/kg
TOXIC EFFECTS :
   Behavioral - analgesia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 52,1340,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 53900 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 52,1340,1987
 
                            *** END OF RECORD ***