*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XO0605000
CHEMICAL NAME           : Thioxanthene,
                          2-chloro-9-(3-(dimethylamino)propylidene)-,
                          hydrochloride, (E)-
CAS REGISTRY NUMBER     : 2461-06-5
LAST UPDATED            : 198706
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C18-H18-Cl-N-S.Cl-H
MOLECULAR WEIGHT        : 352.34
WISWESSER LINE NOTATION : T C666 BS IYJ FG IU3N1&1 &GH -E
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (E)-2-Chloro-9-(3-dimethylaminopropylidene)thioxanthene hydrochloride
   * trans-2-Chloro-9-(3-(dimethylamino)propylidene)thioxanthene,  
   hydrochloride
   * (E)-Chlorprothixene hydrochloride
   * trans-Chlorprothixene hydrochloride
   * trans-N714
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 217 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   15,335,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 114 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   15,335,1959
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 33500 ug/kg
TOXIC EFFECTS :
   Behavioral - ataxia
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 45,3166,1980
 
                            *** END OF RECORD ***