*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XS4375000
CHEMICAL NAME           : p-Toluamide, N-isopropyl-alpha-(2-methylazo)-
CAS REGISTRY NUMBER     : 2235-59-8
BEILSTEIN REFERENCE NO. : 2648551
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H17-N3-O
MOLECULAR WEIGHT        : 219.32
WISWESSER LINE NOTATION : 1Y1&MVR D1NUN1
COMPOUND DESCRIPTOR     : Tumorigen
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * Azo-natulan
   * Benzamide, 4-((methylazo)methyl)-N-(1-methylethyl)-
   * N-Isopropyl-alpha-(2-methylazo)-p-toluamide
   * p-Toluamide, N-isopropyl-alpha-(methylazo)-
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2800 mg/kg/8W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Blood - leukemia
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   42,337,1969
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 255 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - spermatogenesis (incl. genetic material,
   sperm morphology, motility, and count)
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   47,1547,1987
 
                            *** END OF RECORD ***