*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XT6650000
CHEMICAL NAME           : m-Toluenesulfonic acid,
                          6,6'-((4,8-dihydroxy-1,5-anthraquinonylene)diimino)di
                          -, disodium salt
CAS REGISTRY NUMBER     : 3209-30-1
LAST UPDATED            : 199709
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C28-H20-N2-O10-S2.2Na
MOLECULAR WEIGHT        : 654.60
WISWESSER LINE NOTATION : L C666 BV IVJ DQ GMR D1 BSWQ& KQ NMR D1 BSWQ &-NA- 2
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * C.I. 63340
   * Toluidine blue (anthraquinone dye)
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 29 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - other changes
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 10,337,1951
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 28 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - other changes
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 10,337,1951
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 13 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - other changes
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   FEPRA7 Federation Proceedings, Federation of American Societies for
   Experimental Biology. (Bethesda, MD)  V.1-46, 1942-87.
   Volume(issue)/page/year: 10,337,1951
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Sex chromosome loss and nondisjunction
ROUTE OF EXPOSURE       : Unreported
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 500 ppm
REFERENCE :
   14ZYA8 "Induction of Mutations and the Mutation Process, Proceedings of a
   Symposium, Prague, Czechoslovakia, 1963," Veleminsky, J., and T. Gichnar,
   eds., Prague, Academia, 1965  Volume(issue)/page/year: -,115,1965
 
                            *** END OF RECORD ***