*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XU0183500
CHEMICAL NAME           : Toluene, 2,4,6-trinitro-, mixed with
                          hexahydro-1,3,5-trinitro-1,3,5-triazine (1:0.62)
LAST UPDATED            : 199309
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C7-H5-N3-O6.C3-H6-N6-O6
MOLECULAR WEIGHT        : 449.30
WISWESSER LINE NOTATION : T6N CN ENTJ ANW CNW ENW &WNR B1 CNW ENW
SYNONYMS/TRADE NAMES :
   * LAP
   * alpha-TNT mixed with RDX
   * 2,4,6-Trinitrotoluene mixed with hexahydro-1,3,5-trinitro-1,3,5-triazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 574 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Kidney, Ureter, Bladder - hematuria
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 9,587,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 947 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Kidney, Ureter, Bladder - hematuria
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 9,587,1982
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 27937 mg/kg/13W-C
TOXIC EFFECTS :
   Endocrine - changes in spleen weight
   Blood - pigmented or nucleated red blood cells
   Related to Chronic Data - changes in testicular weight
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 9,587,1982
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 42042 mg/kg/13W-C
TOXIC EFFECTS :
   Liver - changes in liver weight
   Endocrine - changes in spleen weight
   Blood - changes in erythrocyte (RBC) count
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 9,587,1982
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 4550 mg/kg/13W-I
TOXIC EFFECTS :
   Liver - changes in liver weight
   Blood - other changes
   Biochemical - Enzyme inhibition, induction, or change in blood or tissue
   levels - transaminases
REFERENCE :
   JTEHD6 Journal of Toxicology and Environmental Health.  (Hemisphere Pub.,
   1025 Vermont Ave., NW, Washington, DC 20005)  V.1-    1975/76-
   Volume(issue)/page/year: 9,587,1982
 
                            *** END OF RECORD ***