*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XU1637000
CHEMICAL NAME           : p-Toluic acid, 3-(bis(2-chloropropyl)amino)-
CAS REGISTRY NUMBER     : 54941-23-0
BEILSTEIN REFERENCE NO. : 2752405
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C14-H19-Cl2-N-O2
MOLECULAR WEIGHT        : 304.24
WISWESSER LINE NOTATION : QVR D1 CN1YG1&1YG1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzoic acid, 3-(N,N-bis(2-chloropropyl)amino)-4-methyl-
   * 3-(Bis(2-chloropropyl)amino)-p-toluic acid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 34 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   CTRRDO Cancer Treatment Reports.  (Washington, DC)  V.60-71, 1976-87.  For
   publisher information,  see JNCIEQ.  Volume(issue)/page/year: 62,2045,1978
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 31 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 18,385,1983
 
                            *** END OF RECORD ***