*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XU5803000
CHEMICAL NAME           : p-Toluidine, N,N-dimethyl-
CAS REGISTRY NUMBER     : 99-97-8
LAST UPDATED            : 199710
DATA ITEMS CITED        : 10
MOLECULAR FORMULA       : C9-H13-N
MOLECULAR WEIGHT        : 135.23
WISWESSER LINE NOTATION : 1N1&R D1
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * Benzenamine, N,N,4-trimethyl-
   * p-(Dimethylamino)toluene
   * Dimethyl-p-toluidine
   * Dimetil-p-toluidina
   * N,N,4-Trimethylaniline
   * p,N,N-Trimethylaniline
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 212 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AISFAR Archivio Italiano di Scienze Farmacologiche.  (Modena, Italy) V.1-11,
   1932-42; Series 2: V.1-3, 1948-50; Series 3: V.1-15, 1951-65. Discontinued. 
   Volume(issue)/page/year: 1,284,1951
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA damage
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 1082 mg/kg
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   21,349,1993
 
TYPE OF TEST            : DNA damage
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 541 mg/kg
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   21,349,1993
 
TYPE OF TEST            : DNA damage
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 135 mg/kg
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   21,349,1993
 
TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 900 umol/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   21,349,1993

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M3033
       No. of Facilities: 2356 (estimated)
       No. of Industries: 29
       No. of Occupations: 19
       No. of Employees: 31063 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M3033
       No. of Facilities: 2570 (estimated)
       No. of Industries: 42
       No. of Occupations: 43
       No. of Employees: 62720 (estimated)
       No. of Female Employees: 27118 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NIOSH Analytical Method, 1994: Amines, aromatic, 2002

 
                            *** END OF RECORD ***