*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XW5865000
CHEMICAL NAME           : Toxin, mushroom, amanita phalloides
CAS REGISTRY NUMBER     : 39412-56-1
LAST UPDATED            : 198909
DATA ITEMS CITED        : 3
COMPOUND DESCRIPTOR     : Natural Product
SYNONYMS/TRADE NAMES :
   * Amanita phalloides toxin
   * Phallolysin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 ug/kg
TOXIC EFFECTS :
   Blood - other hemolysis with or without anemia
REFERENCE :
   TOXIA6 Toxicon.  (Pergamon Press Ltd., Headington Hill Hall, Oxford OX3 OBW,
   UK)  V.1-    1962-  Volume(issue)/page/year: 17(Suppl 1),165,1979
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AGACBH Agents and Actions, A Swiss Journal of Pharmacology.  (Birkhaeuser
   Verlag, POB 133, CH-4010 Basel, Switzerland)  V.1-    1969/70-
   Volume(issue)/page/year: 2,142,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 123 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Kidney, Ureter, Bladder - other changes
REFERENCE :
   NSAPCC Naunyn-Schmiedeberg's Archives of Pharmacology.  (Springer Verlag,
   Heidelberger, Pl. 3, D-1000 Berlin 33, Fed. Rep. Ger.)  V.272-    1972-
   Volume(issue)/page/year: 290,133,1975
 
                            *** END OF RECORD ***