*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XW7750000
CHEMICAL NAME           : Tragacanth gum
CAS REGISTRY NUMBER     : 9000-65-1
LAST UPDATED            : 199701
DATA ITEMS CITED        : 7
COMPOUND DESCRIPTOR     : Natural Product
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * Gum tragacanth
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 3050 ug/24H
REACTION SEVERITY       : Mild
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 6(1),1,1987
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 610 ug
REACTION SEVERITY       : Mild
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 6(1),1,1987
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10200 mg/kg
TOXIC EFFECTS :
   Behavioral - ataxia
   Kidney, Ureter, Bladder - urine volume increased
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 6(1),1,1987
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FDRLI* Food & Drug Research Laboratories, Inc., Papers.  (P.O. Box 107, Rt.
   17C, Waverly, NY 14892-0107)  Volume(issue)/page/year: 124,-,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 7200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FDRLI* Food & Drug Research Laboratories, Inc., Papers.  (P.O. Box 107, Rt.
   17C, Waverly, NY 14892-0107)  Volume(issue)/page/year: 124,-,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - hamster
DOSE/DURATION           : 8800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FDRLI* Food & Drug Research Laboratories, Inc., Papers.  (P.O. Box 107, Rt.
   17C, Waverly, NY 14892-0107)  Volume(issue)/page/year: 124,-,1976

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***