*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XY4200000
CHEMICAL NAME           : s-Triazine, 2,4-bis(isopropylamino)-6-methoxy-
CAS REGISTRY NUMBER     : 1610-18-0
BEILSTEIN REFERENCE NO. : 0613574
LAST UPDATED            : 199707
DATA ITEMS CITED        : 13
MOLECULAR FORMULA       : C10-H19-N5-O
MOLECULAR WEIGHT        : 225.34
WISWESSER LINE NOTATION : T6N CN ENJ BO1 DMY1&1 FMY1&1
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Mutagen
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * 2,4-Bis(isopropylamino)-6-methoxy-s-triazine
   * 2,6-Diisopropylamino-4-methoxytriazine
   * N,N'-Diisopropyl-6-methoxy-1,3,5-triazine-2,4-diyldiamine
   * G-31435
   * Gesafram
   * Gesafram 50
   * 2-Methoxy-4,6-bis(isopropylamino)-s-triazine
   * 2-Methoxy-4,6-bis(isopropylamino)-1,3,5-triazine
   * Methoxypropazine
   * Pramitol 5P
   * Prometon
   * Prometone
   * 1,3,5-Triazine-2,4-diamine, 6-methoxy-N,N'-bis(1-methylethyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Open irritation test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 105 mg
REACTION SEVERITY       : Mild
REFERENCE :
   CIGET* Ciba-Geigy Toxicology Data/Indexes.  (Ciba-Geigy Corp., 556 Morris
   Ave., Summit, NJ 07901)  Volume(issue)/page/year: -,-,1977
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 21 mg
REACTION SEVERITY       : Moderate
REFERENCE :
   CIGET* Ciba-Geigy Toxicology Data/Indexes.  (Ciba-Geigy Corp., 556 Morris
   Ave., Summit, NJ 07901)  Volume(issue)/page/year: -,-,1977
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 503 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   7,299,1986
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 36 gm/m3/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FMCHA2 Farm Chemicals Handbook.  (Meister Pub., 37841 Euclid Ave.,
   Willoughy, OH 44094)  Volume(issue)/page/year: -,C246,1991
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >2500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year:
   7,299,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2160 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PCOC** Pesticide Chemicals Official Compendium, Association of the American
   Pesticide Control Officials, Inc., 1966.  (Topeka, KS)
   Volume(issue)/page/year: -,931,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GUCHAZ Guide to the Chemicals Used in Crop Protection.  (Information Canada,
   171 Slater St., Ottawa, Ont., Canada)  Volume(issue)/page/year: 6,425,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - domestic
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CIGET* Ciba-Geigy Toxicology Data/Indexes.  (Ciba-Geigy Corp., 556 Morris
   Ave., Summit, NJ 07901)  Volume(issue)/page/year: -,-,1977
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Specific locus test
ROUTE OF EXPOSURE       : Multiple routes
TEST SYSTEM             : Insect - Drosophila melanogaster
DOSE/DURATION           : 1000 ppm
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   25,148,1995

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   54,7740,1989

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 84758
       No. of Facilities: 389 (estimated)
       No. of Industries: 5
       No. of Occupations: 14
       No. of Employees: 1566 (estimated)
       No. of Female Employees: 114 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   On EPA IRIS database

 
                            *** END OF RECORD ***