*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XY5950000
CHEMICAL NAME           : s-Triazine,
                          4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3,4-dichlorob
                          enzyloxy)-, hydrochloride
CAS REGISTRY NUMBER     : 22242-55-3
OTHER CAS REGISTRY NOS. : 23573-50-4
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H15-Cl2-N5-O.Cl-H
MOLECULAR WEIGHT        : 352.68
WISWESSER LINE NOTATION : T6N CN EN BHJ AO1R CG DG& B1 B1 DZ FZ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * BRL 50216
   * Clociquanil hydrochloride
   *   4,6-Diamino-1,2-dihydro-2,2-dimethyl-1-(3,4-dichlorobenzyloxy)-1,3,5-tri
     azine hydrochloride
   * 1,3,5-Triazine-2,4-diamine,  
   1-((3,4-dichlorophenyl)methoxy)-1,6-dihydro-6,6-dimethyl-, HCl
   * WR 38839
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   27,271,1974
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 315 mg/kg/21D-I
TOXIC EFFECTS :
   Gastrointestinal - hypermotility, diarrhea
   Gastrointestinal - nausea or vomiting
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   PHMCAA Pharmacologist.  (American Soc. for Pharmacology and Experimental
   Therapeutics, 9650 Rockville Pike, Bethesda, MD 20014)  V.1-    1959-
   Volume(issue)/page/year: 15,226,1973
 
                            *** END OF RECORD ***