*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : XY6895000 CHEMICAL NAME : s-Triazine, 4,6-diamino-2-(5-nitro-2-furyl)- CAS REGISTRY NUMBER : 720-69-4 BEILSTEIN REFERENCE NO. : 0251037 REFERENCE : 4-27-00-09447 (Beilstein Handbook Reference) LAST UPDATED : 199709 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C7-H6-N6-O3 MOLECULAR WEIGHT : 222.19 WISWESSER LINE NOTATION : T6N CN ENJ BZ DZ F- BT5OJ ENW COMPOUND DESCRIPTOR : Tumorigen Mutagen SYNONYMS/TRADE NAMES : * 4,6-Diamino-2-(5-nitro-2-furyl)-s-triazine * 1,3,5-Triazine-2,4-diamine, 6-(5-nitro-2-furyl)- *** HEALTH HAZARD DATA *** ** TUMORIGENIC DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 13 gm/kg/46W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Skin and Appendages - tumors REFERENCE : JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 51,403,1973 ** MUTATION DATA ** TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 100 ng/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 40,9,1976 TYPE OF TEST : DNA repair TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 500 nmol/well REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 34,2266,1974 TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 300 nmol/well REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 34,2266,1974 TYPE OF TEST : DNA repair TEST SYSTEM : Bacteria - Escherichia coli DOSE/DURATION : 500 nmol/well REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 34,2266,1974 *** REVIEWS *** TOXICOLOGY REVIEW CCSUDL Carcinogenesis--A Comprehensive Survey. (Raven Press, 1185 Ave. of the Americas, New York, NY 10036) V.1- 1976- Volume(issue)/page/year: 4,171,1978 *** STATUS IN U.S. *** EPA GENETOX PROGRAM 1988, Positive: Histidine reversion-Ames test *** END OF RECORD ***