*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XZ4095000
CHEMICAL NAME           : 1H-1,2,4-Triazole, 1-benzyl-
CAS REGISTRY NUMBER     : 6085-94-5
BEILSTEIN REFERENCE NO. : 0118646
REFERENCE               : 5-26-01-00148 (Beilstein Handbook Reference)
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H9-N3
MOLECULAR WEIGHT        : 159.21
WISWESSER LINE NOTATION : T5NN DNJ A1R
COMPOUND DESCRIPTOR     : Drug
                          Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 1-Benzyl-1,2,4-triazole
   * 1-Benzyl-1H-1,2,4-triazole
   * L-22080
   * 1H-1,2,4-Triazole, 1-(phenylmethyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 720 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
   Behavioral - somnolence (general depressed activity)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 121,443,1959
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - hamster
DOSE                    : 250 ug/kg
SEX/DURATION            : female 4-8 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - other measures of fertility
REFERENCE :
   RDMIDP Quarterly Reviews on Drug Metabolism and Drug Interactions.  (Freund
   Pub. House, Suite 500, Chesham House, 150 Regent St., London W1R 5FA, UK)
   V.3-    1980-  Volume(issue)/page/year: 4,237,1982
 
                            *** END OF RECORD ***