*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XZ3018500
CHEMICAL NAME           : s-Triazin-2(1H)-one,
                          5,6-dihydro-4-amino-1-beta-D-ribofuranosyl-
CAS REGISTRY NUMBER     : 62488-57-7
LAST UPDATED            : 199709
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C8-H14-N4-O5
MOLECULAR WEIGHT        : 246.26
WISWESSER LINE NOTATION : T6NVN EN DHJ EZ C- BT5OTJ CQ DQ E1Q
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 4-Amino-5,6-dihydro-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one
   * 5,6-Dihydro-4-amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one
   * 5,6-Dihydro-5-azacytidine
 
                       *** HEALTH HAZARD DATA ***
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Microorganism - not otherwise specified
DOSE/DURATION           : 100 mg/L
REFERENCE :
   ICDBEO In Vitro Cellular and Developmental Biology.  (Tissue Culture Assoc.,
   19110 Montgomery Village Ave., Suite 300, Gaithersburg, MD 20879) V.21-   
   1985-  Volume(issue)/page/year: 24,1114,1988
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 100 mg/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,5511,1986
 
TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 10 umol/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 16,1647,1995
 
TYPE OF TEST            : DNA damage
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 10 mg/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   46,5511,1986
 
TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Lymphocyte
DOSE/DURATION           : 50 umol/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 10,2003,1989
 
TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - mouse Embryo
DOSE/DURATION           : 30 umol/L
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   42,817,1982
 
                            *** END OF RECORD ***