*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XZ3018600
CHEMICAL NAME           : 1,3,5-Triazin-2(1H)-one,
                          5,6-dihydro-4-amino-1-beta-D-ribofuranosyl-,
                          monohydrochloride
CAS REGISTRY NUMBER     : 62402-31-7
LAST UPDATED            : 199409
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C8-H14-N4-O5.Cl-H
MOLECULAR WEIGHT        : 282.72
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-Amino-5,6-dihydro-1-beta-D-ribofuranosyl-1,3,5-triazin-2(1H)-one  
   hydrochloride
   * 5,6-Dihydro-4-amino-1-beta-D-ribofuranosyl-1,3,5-triazin-2(1H)-one  
   hydrochloride
   * Dihydro-5-azacytidine hydrochloride
   * 5,6-Dihydro-5-azacytidine hydrochloride
   * 4-Imino-1-beta-D-ribofuranosyltetrahydro-2(1H)-triazin-2-one  
   hydrochloride
   * NSC-264880
   * 2(1H)-s-Triazin-2-one, tetrahydro-4-imino-1-beta-D-ribofuranosyl-,  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2559 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB82-195751
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   INNDDK Investigational New Drugs. The Journal of New Anticancer Agents.
   Kluwer Academic Pub., POB 358, Accord Stn., Hingham, MA 02018)  V.1- 1983- 
   Volume(issue)/page/year: 1,47,1983
 
                            *** END OF RECORD ***