*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XZ5478120
CHEMICAL NAME           : 4H-(1,2,4)Triazolo(4,3-a)(1,5)benzodiazepin-5-amine,
                          1-phenyl-N,N,4-trimethyl-
CAS REGISTRY NUMBER     : 133118-18-0
BEILSTEIN REFERENCE NO. : 4204004
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H19-N5
MOLECULAR WEIGHT        : 317.43
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   N,N,4-Trimethyl-1-phenyl-4H-(1,2,4)triazolo(4,3-a)(1,5)benzodiazepin-5-a
     mine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 980 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 25,681,1990
 
                            *** END OF RECORD ***