*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XZ5472163
CHEMICAL NAME           : 4H-(1,2,4)Triazolo(4,3-a)(1,4)benzodiazepine,
                          8-bromo-6-(2-chlorophenyl)-1-((methylthio) methyl)-
CAS REGISTRY NUMBER     : 87245-49-6
BEILSTEIN REFERENCE NO. : 4580033
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C18-H14-Br-Cl-N4-S
MOLECULAR WEIGHT        : 433.78
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   8-Bromo-6-(2-chlorophenyl)-1-(methylthiomethyl)-4H-s-triazolo(4,3-a)-1,4
     -benzodiazepine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   CCCCAK Collection of Czechoslovak Chemical Communications.  (Academic Press
   Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK)  V.1-    1929-
   Volume(issue)/page/year: 48,1477,1983
 
                            *** END OF RECORD ***