*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : XZ5478460 CHEMICAL NAME : s-Triazolo(5,1-a)isoquinoline, 5,6-dihydro-2-(p-chlorophenyl)- CAS REGISTRY NUMBER : 55308-60-6 BEILSTEIN REFERENCE NO. : 0619966 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C16-H12-Cl-N3 MOLECULAR WEIGHT : 281.76 COMPOUND DESCRIPTOR : Reproductive Effector SYNONYMS/TRADE NAMES : * 2-(p-Chlorophenyl)-5,6-dihydro-s-triazolo(5,1-a)isoquinoline * L 10506 * (1,2,4)Triazolo(5,1-a)isoquinoline, 2-(4-chlorophenyl)-5,6-dihydro- *** HEALTH HAZARD DATA *** ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE : 100 mg/kg SEX/DURATION : female 6-10 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : RDMIDP Quarterly Reviews on Drug Metabolism and Drug Interactions. (Freund Pub. House, Suite 500, Chesham House, 150 Regent St., London W1R 5FA, UK) V.3- 1980- Volume(issue)/page/year: 4,237,1982 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - hamster DOSE : 12500 ug/kg SEX/DURATION : female 4-8 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : JOPHDQ Journal of Pharmacobio-Dynamics. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1978- Volume(issue)/page/year: 5,55,1982 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - hamster DOSE : 325 ug/kg SEX/DURATION : female 4-8 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) REFERENCE : JOPHDQ Journal of Pharmacobio-Dynamics. (Japan Pub. Trading Co. (USA), 1255 Howard St., San Francisco, CA 94103) V.1- 1978- Volume(issue)/page/year: 5,55,1982 *** END OF RECORD ***