*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XZ3880000
CHEMICAL NAME           : s-Triazole, 3-amino-4-methyl-5-(5-nitro-2-furyl)-
CAS REGISTRY NUMBER     : 10187-86-7
LAST UPDATED            : 199709
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C7-H7-N5-O3
MOLECULAR WEIGHT        : 209.19
WISWESSER LINE NOTATION : T5NN DNJ CZ D1 E- BT5OJ ENW
COMPOUND DESCRIPTOR     : Human
SYNONYMS/TRADE NAMES :
   * 3-Amino-4-methyl-5-(5-nitro-2-furyl)-s-triazole
   * 4H-1,2,4-Triazol-3-amine, 4-methyl-5-(5-nitro-2-furyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 126 mg/kg
TOXIC EFFECTS :
   Musculoskeletal - joints
   Immunological Including Allergic - other immediate (humoral): urticaria,
   allergic rhinitis, serum sickness
   Nutritional and Gross Metabolic - body temperature increase
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 16,312,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1460 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 16,312,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 730 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 16,312,1973
 
                            *** END OF RECORD ***