*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XZ6157850
CHEMICAL NAME           : 1,2,4-Triazolo(4,3-a)pyrimidin-3(2H)-one,
                          5,6,7,8-tetrahydro-2-phenyl-
CAS REGISTRY NUMBER     : 105896-19-3
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C11-H12-N4-O
MOLECULAR WEIGHT        : 216.27
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 5,6,7,8-Tetrahydro-2-phenyl-1,2,4-triazolo(4,3-a)pyrimidin-3(2H)-one
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 45,288,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 375 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 45,288,1988
 
                            *** END OF RECORD ***