*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XZ5705000
CHEMICAL NAME           : (1,2,4)Triazolo(1,5-c)pyrimidin-5-amine,
                          8-(2-ethoxyethyl)-7-phenyl-
CAS REGISTRY NUMBER     : 88133-11-3
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C15-H17-N5-O
MOLECULAR WEIGHT        : 283.37
SYNONYMS/TRADE NAMES :
   * Bemitradine
   * 8-(2-Ethoxyethyl)-7-phenyl-(1,2,4)triazolo(1,5-c)pyrimidin-5-amine
   * SC 33643
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 80080 mg/kg/52W-I
TOXIC EFFECTS :
   Liver - changes in liver weight
   Blood - changes in platelet count
   Related to Chronic Data - death
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 10,443,1991
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7 gm/kg/7D-I
TOXIC EFFECTS :
   Cardiac - other changes
   Endocrine - other changes
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   JACTDZ Journal of the American College of Toxicology.  (Mary Ann Liebert,
   Inc., 1651 Third Ave., New York, NY 10128)  V.1-12, 1982-1993. Discontinued.
    Volume(issue)/page/year: 10,511,1991
 
                            *** END OF RECORD ***