*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : XZ5718000
CHEMICAL NAME           : 3H-1,2,3-Triazolo(4,5-d)pyrimidin-7-amine,
                          3-beta-D-ribofuranosyl-
CAS REGISTRY NUMBER     : 10299-44-2
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H12-N6-O4
MOLECULAR WEIGHT        : 268.27
COMPOUND DESCRIPTOR     : Mutagen
SYNONYMS/TRADE NAMES :
   * 8-Azaadenosine
   * 3-beta-D-Ribofuranosyl-3H-1,2,3-triazolo(4,5-d)pyrimidin-7-amine
   * 3H-v-Triazolo(4,5-d)pyrimidine, 7-amino-3-beta-D-ribofuranosyl-
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 169 mg/kg/5D-I
TOXIC EFFECTS :
   Endocrine - hypoglycemia
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
   Related to Chronic Data - death
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   31,2415,1982
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 10 umol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   31,3207,1982
 
                            *** END OF RECORD ***