*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YK4570000
CHEMICAL NAME           : Triphosphoric acid, pentasodium salt
CAS REGISTRY NUMBER     : 7758-29-4
LAST UPDATED            : 199712
DATA ITEMS CITED        : 15
MOLECULAR FORMULA       : O10-P3.5Na
MOLECULAR WEIGHT        : 367.86
WISWESSER LINE NOTATION : NA5 P3-O5
SYNONYMS/TRADE NAMES :
   * Armofos
   * Empiphos stp-D
   * Natriumtripolyphosphat
   * Pentasodium triphosphate
   * Pentasodium tripolyphosphate
   * Polygon
   * Rhodiaphos LV
   * S 400
   * Sodium phosphate (Na5P3O10)
   * Sodium triphosphate
   * Sodium triphosphate (Na5P3O10)
   * Sodium tripolyphosphate
   * STPP
   * Thermphos
   * Thermphos L 50
   * Thermphos N
   * Thermphos SPR
   * Tripoly
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3120 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - coma
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0545589
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 525 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 108,117,1953
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2060 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VLUBB6 Vestnik Leningradskogo Universiteta, Biologiya.  Journal of Leningrad
   University, Biology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  No.1-
      1956-  Volume(issue)/page/year: (3),97,1984
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3100 mg/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 38(9),19,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
REFERENCE :
   REPMBN Revue d'Epidemiologie, Medecine Sociale et Sante Publique.  (Masson
   Editeur, 120 Blvd. Saint-Germain, F-75280 Paris Cedex O6, France)  V.1-
   1953-  Volume(issue)/page/year: 10,391,1962
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 7,445,1957
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 71 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 7,445,1957
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   VLUBB6 Vestnik Leningradskogo Universiteta, Biologiya.  Journal of Leningrad
   University, Biology. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  No.1-
      1956-  Volume(issue)/page/year: (3),97,1984
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2730 mg/kg/13W-I
TOXIC EFFECTS :
   Endocrine - changes in spleen weight
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 38(9),19,1973

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   54,7740,1989

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 80076
       No. of Facilities: 101624 (estimated)
       No. of Industries: 308
       No. of Occupations: 153
       No. of Employees: 930493 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 80076
       No. of Facilities: 49146 (estimated)
       No. of Industries: 268
       No. of Occupations: 169
       No. of Employees: 943961 (estimated)
       No. of Female Employees: 347961 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8786;8EHQ-0892-8869
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***