*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YM2781500
CHEMICAL NAME           : 2-Tropanecarboxamide, N,N-diethyl-3-hydroxy-,
                          benzoate, hydrochloride
LAST UPDATED            : 198909
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H28-N2-O3.Cl-H
MOLECULAR WEIGHT        : 380.96
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * (+)-2-(N,N-Diethylcarboxamido)-3-benzoxytropane hydrochloride
   * N,N-Diethyl-3-hydroxy-2-tropanecarboxamide benzoate hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4800 ug/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 115,452,1958
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Cardiac - arrhythmias (including changes in conduction)
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 115,452,1958
 
                            *** END OF RECORD ***