*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : YM4375200 CHEMICAL NAME : 1-alpha-H,5-alpha-H-Tropan-3-alpha-ol, 2-(p-chlorophenyl)-2-phenylacetate, hydrochloride CAS REGISTRY NUMBER : 74051-40-4 LAST UPDATED : 199012 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C22-H24-Cl-N-O2.Cl-H MOLECULAR WEIGHT : 406.38 WISWESSER LINE NOTATION : T56 A ANTJ A1 CR DG& DOV1R &GH COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * Acetic acid, (p-chlorophenyl)phenyl-, tropan-3-yl ester hydrochloride * p-Chlorodiphenylacetyltropeine hydrochloride * Chlorotropacin, hydrochloride * DF 303 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 310 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Kidney, Ureter, Bladder - hematuria REFERENCE : BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 14,559,1959 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 48 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : RPTOAN Russian Pharmacology and Toxicology (English Translation). Translation of FATOAO. (Euromed Pub., 33, Woodlands Rd., Surbiton, Surrey, UK) V.30- 1967- Volume(issue)/page/year: 36,16,1973 *** END OF RECORD ***