*** CHEMICAL IDENTIFICATION *** RTECS NUMBER : YM3550000 CHEMICAL NAME : 1-alpha-H,5-alpha-H-Tropanium, 8-(p-chlorobenzyl)-3-hydroxy-, bromide, p-aminobenzilate (ester) CAS REGISTRY NUMBER : 63977-81-1 LAST UPDATED : 199109 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C22-H26-Cl-N2-O2.Br MOLECULAR WEIGHT : 465.86 WISWESSER LINE NOTATION : T56 A AKTJ A1 A1R DG& GOVXQR&R DZ &Q &E COMPOUND DESCRIPTOR : Drug SYNONYMS/TRADE NAMES : * p-Chlorobenzyl-p-aminobenzoyltropinium bromide * N-266 *** HEALTH HAZARD DATA *** ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2500 ug/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Lungs, Thorax, or Respiration - other changes REFERENCE : APACAB Acta Physiologica Academiae Scientiarum Hungaricae. (Budapest, Hungary) V.1-60, 1950-82. Volume(issue)/page/year: 4,341,1953 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 35 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 32ZCAI "Ganglion-Blocking and Ganglion-Stimulation Agents," Kharkevich, D.A., Moscow, First Moscow Medical Institute, 1967 Volume(issue)/page/year: -,71,1967 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 5 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Lungs, Thorax, or Respiration - other changes REFERENCE : APACAB Acta Physiologica Academiae Scientiarum Hungaricae. (Budapest, Hungary) V.1-60, 1950-82. Volume(issue)/page/year: 4,341,1953 *** END OF RECORD ***