*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YM6045000
CHEMICAL NAME           : 1-alpha-H,5-alpha-H-Tropan-3-beta-ol, m-tolylacetate,
                          hydrochloride
CAS REGISTRY NUMBER     : 3266-14-6
LAST UPDATED            : 199106
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H23-N-O2.Cl-H
MOLECULAR WEIGHT        : 309.87
WISWESSER LINE NOTATION : T56 A ANTJ A1 GOV1R C1 &GH
SYNONYMS/TRADE NAMES :
   * 3-psi-Tropine m-tolylacetate hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 32700 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   5,625,1963
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 17 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - ataxia
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   5,625,1963
 
                            *** END OF RECORD ***