*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YN7000000
CHEMICAL NAME           : Tryptophan, 5-hydroxy-
CAS REGISTRY NUMBER     : 56-69-9
LAST UPDATED            : 199701
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C11-H12-N2-O3
MOLECULAR WEIGHT        : 220.25
WISWESSER LINE NOTATION : T56 BMJ D1YZVQ GQ
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * 5-Htp
   * Hydroxytryptophan
   * 5-Hydroxytryptophan
   * 5-Hydroxytryptophane
   * 5-Hydroxytrytophan
   * NCI-C56644
   * USAF CB-96
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 200 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 30 mg/kg
SEX/DURATION            : male 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - mating performance (e.g. # sperm positive females
   per # females mated; # copulations per # estrus cycles)
REFERENCE :
   ANENAG Annales d'Endocrinologie.  (Masson Editeur, 120 Blvd. Saint-Germain,
   F-25280 Paris Cedex 06, France)  V.1-    1939-  Volume(issue)/page/year:
   24(Suppl 3),1,1963

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   CLPTAT Clinical Pharmacology and Therapeutics (St. Louis).  (C.V. Mosby Co.,
   11830 Westline Industrial Dr., St. Louis, MO 63146)  V.1-    1960-
   Volume(issue)/page/year: 5,480,1964

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***