*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YP2890000
CHEMICAL NAME           : Tyrosine, alpha-methyl-
CAS REGISTRY NUMBER     : 658-48-0
BEILSTEIN REFERENCE NO. : 2938704
REFERENCE               : 4-14-00-02453 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C10-H13-N-O3
MOLECULAR WEIGHT        : 195.24
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * H 9/88
   * alpha-Methyltyrosine
   * alpha-Methyl-p-tyrosine
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 28 gm/kg/4W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
   Related to Chronic Data - death
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   28,435,1970

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***