*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YP2895000
CHEMICAL NAME           : Tyrosine, alpha-methyl-, methyl ester, hydrochloride
CAS REGISTRY NUMBER     : 1421-66-5
LAST UPDATED            : 199506
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C11-H15-N-O3.Cl-H
MOLECULAR WEIGHT        : 245.73
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * H 44/68
   * alpha-Methyltyrosine methyl ester hydrochloride
   * alpha-Methyl-p-tyrosine methyl ester hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 16800 mg/kg/4W-I
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
   Related to Chronic Data - death
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   28,435,1970
 
                            *** END OF RECORD ***