*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : YM3710000
CHEMICAL NAME           : 1-alpha-H,5-alpha-H-Tropanium,
                          3-alpha-hydroxy-8-methyl-, bromide, 2-propylvalerate
CAS REGISTRY NUMBER     : 80-50-2
LAST UPDATED            : 199504
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C17-H32-N-O2.Br
MOLECULAR WEIGHT        : 362.41
WISWESSER LINE NOTATION : T56 A AKTJ A1 A1 GOVY3&3 &E
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Anisotropine methobromide
   * Anisotropine methylbromide
   * 8-Azoniabicyclo(3.2.1)octane,  
   8,8-dimethyl-3-((1-oxo-2-propylpentyl)oxy)-, bromide, endo-
   * 3-alpha-Hydroxy-8-methyl-1-alpha-H,5-alpha-H-tropanium bromide  
   2-propylvalerate
   * Lytispasm
   * 8-Methyl-3-(2-propylpentanoyloxy)tropinium bromide
   * 8-Methyltropinium bromide 2-propylvalerate
   * Octatropine methylbromide
   * 2-Propylpentanoyltropinium methylbromide
   * Valpin
   * Vapin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 705 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,24,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 850 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,24,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 129 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,24,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 133 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NIIRDN Drugs in Japan (Ethical Drugs).  (Yakugyo Jiho Co., Ltd., Tokyo,
   Japan)  Volume(issue)/page/year: 6,24,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6300 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   OYYAA2 Oyo Yakuri.  Pharmacometrics.  (Oyo Yakuri Kenkyukai, CPO Box 180,
   Sendai 980-91, Japan) V.1-    1967-  Volume(issue)/page/year: 2,70,1968

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M2759
       No. of Facilities: 10 (estimated)
       No. of Industries: 1
       No. of Occupations: 1
       No. of Employees: 197 (estimated)
       No. of Female Employees: 59 (estimated)

 
                            *** END OF RECORD ***